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In clinical studies, the most commonly reported side effect was vomiting.

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Nefazodone, a mixed SSRI and norepinephrine reuptake inhibitor, is a potent CYP3A4 inhibitor and should be avoided in transplant patients due to the potential for severe toxicity.

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This double-blind, placebo-controlled trial of inhaled cyclosporine given in addition to conventional immunosuppression after lung transplantation was negative with respect to its primary end point, since rates of acute rejection were similar in the group receiving cyclosporine and that receiving placebo.

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